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Research Letter
February 15, 2017

Value of Cardiovascular Magnetic Resonance Imaging–Derived Baseline Left Ventricular Ejection Fraction and Volumes for Precise Risk Stratification of Patients With Ischemic CardiomyopathyInsights From the Surgical Treatment for Ischemic Heart Failure (STICH) Trial

Author Affiliations
  • 1Department of Medicine/Cardiology, University of California, Riverside School of Medicine, Riverside
  • 2Department of Medicine/Cardiology, Loma Linda University, Loma Linda, California
  • 3Department of Medicine/Cardiology, Montréal Heart Institute, Université de Montréal, Montréal, Quebec, Canada
  • 4Duke Clinical Research Institute, Durham, North Carolina
  • 5Department of Medicine-Cardiology, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina
  • 6Department of Biostatistics and Bioinformatics, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina
  • 7Department of Medicine/Cardiology, University of Alabama at Birmingham
  • 8University of Southern California, Los Angeles
JAMA Cardiol. Published online February 15, 2017. doi:10.1001/jamacardio.2016.5492

Ischemic cardiomyopathy accounts for approximately 50% of patients with heart failure and one-third of the patients undergoing coronary artery bypass surgery.1 Left ventricular (LV) ejection fraction (EF) and end-systolic volume index (ESVI) are predictors of mortality in these patients. Cardiovascular magnetic resonance (CMR) imaging can provide precise estimates of LV volumes and function. In the Surgical Treatment for Ischemic Heart Failure (STICH) Trial population,2 we tested the hypothesis that CMR-derived LVEF and volumes would provide improved risk stratification.

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