This Viewpoint discusses and compares the outcomes of the SPRINT and the HOPE-3 blood pressure trial.
This Viewpoint compares 5 recent randomized clinical trials of blood pressure lowering involving high- and intermediate-risk participants.
This Editorial discusses the US Preventive Services Task Force recommendation statement on screening for lipid disorders in children and adolescents and why this screening is important.
This study uses NHANES data to assess the representativeness of the findings of SPRINT and the HOPE-3 trial to US patients and to explore the cardiovascular disease risk profiles of various populations with elevated systolic blood pressure.
This cost-effectiveness analysis evaluates the incremental cost-effectiveness of intensive blood pressure management compared with standard management in patients with hypertension.
This study describes the diagnostic accuracy of technetium 99m pyrophosphate cardiac imaging for detecting transthyretin cardiac amyloidosis in patient with suspected disease.
This study uses data from the Nationwide Inpatient Sample to assess the temporal trends, predictors, and outcomes of performing coronary angiography and percutaneous coronary intervention in patients resuscitated after out-of-hospital cardiac arrest with initial rhythms of ventricular tachycardia or pulseless ventricular fibrillation.
This cohort study examines the adoption of subcutaneous implantable cardioverter
defibrillators (ICDs) into clinical practice in the United States, and compares
in-hospital outcomes with those of patients undergoing transvenous ICD
This study (the Advantageous Predictors of Acute Coronary Syndrome Evaluation Study) compares the use of a uniform cutoff level with sex-specific cutoff levels of high-sensitivity coronary troponin T in the diagnosis of acute myocardial infarction.
This multicenter clinical trial evaluates the safety of preoperative use of ticagrelor with or without aspirin in patients with acute coronary syndromes undergoing isolated coronary artery bypass grafting compared with aspirin alone.
This cohort study investigates associations between depressive disorders and incident acute myocardial infarction in US veterans with human immunodeficiency virus infection.
This cohort study compares outcomes of women vs men with structural heart disease undergoing ventricular tachycardia ablation.
This study evaluates patients in the randomized CoreValve US Pivotal High-risk Trial with a Society of Thoracic Surgeons Predictor of Mortality score of 7% or less to determine the benefit of transcatheter aortic valve replacement in lower-risk patients.
In this Special Communication, FDA Commissioner Robert Califf proposes ways to scale up the national cardiovascular research enterprise through use of interoperable clinical and trial data registries and broadly distributed learning networks.
This review discusses barriers to the clinical implementation of stem cell therapy in patients with cardiovascular disease as well as potential strategies to overcome them.
A woman with end-stage lung disease secondary to systemic sclerosis and pulmonary hypertension underwent bilateral sequential lung transplantation without cardiopulmonary bypass through a clamshell thoracotomy and after the operation developed seizures when ambulating. What is your diagnosis?