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The Cutting Edge: Challenges in Medical and Surgical Therapies
Sep 2011

Autologous Noncultured Melanocyte-Keratinocyte Transplantation Procedure in an African American Man With Postburn Leukoderma

Arch Dermatol. 2011;147(9):1025-1028. doi:10.1001/archdermatol.2011.238

Postburn leukoderma can cause significant distress for patients. Unfortunately, there are limited options for the treatment of postburn leukoderma.

A 26-year-old African American man was seen at the Dermatology Department at Henry Ford Hospital (Detroit, Michigan) complaining of leukoderma secondary to second- and third-degree burns involving more than 85% of his body. The injuries resulted from a car crash and subsequent fire 9 years earlier. Previous treatments included partial-thickness skin grafts, contracture releases, and scar revisions. While our patient had significant functional morbidities secondary to his accident, he noted postburn leukoderma as a major area of concern. He reported that the depigmented areas of the face, chest, and lower extremities were distressing and affected his social interactions. Consequently, he sought treatment to restore his natural skin color.

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