Author Affiliations: Departments of Dermatology and Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Lichen sclerosus (LS) is an autoimmune inflammatory dermatosis that most commonly afflicts the female genitalia, with an estimated prevalence of 1 in 300 to 1 in 1000. An increased frequency of autoimmune disorders, including thyroid disease, vitiligo, alopecia areata, and pernicious anemia, occurs in patients with vulvar LS compared with controls.1 A diagnosis of LS should prompt evaluation for other autoimmune diseases, but what conditions should prompt physicians to investigate for genital LS?
Schlosser BJ. Missing Genital Lichen Sclerosus in Patients With Morphea: Don't Ask? Don't Tell?Comment on “High Frequency of Genital Lichen Sclerosus in a Prospective Series of 76 Patients With Morphea ”. Arch Dermatol. 2012;148(1):28-29. doi:10.1001/archdermatol.2011.2097