Author Affiliations: Dipartimento di Anestesiologia, Terapia Intensiva e Scienze Dermatologiche, Universit à degli Studi di Milano-Fondazione IRCCS Ca ’ Granda, Ospedale Maggiore Policlinico, Milano, Italy.
Syphilis is an infectious disease caused by Treponema pallidum and characterized by cutaneous, mucous, and systemic involvement.1 The course is chronic and arbitrarily divided into different stages2: the first is defined by a chancre localized at the site of T pallidum inoculation, while secondary syphilis can present with a cutaneous polymorphic eruption, mucous lesions, diffuse lymphadenopathy, and systemic symptoms.1
Ramoni S, Cusini M, Crosti C. An Atlas of Syphilis in a Single Case. Arch Dermatol. 2011;147(7):869-870. doi:10.1001/archdermatol.2011.175