SECTION EDITOR: MARY S. STONE, MD; ASSISTANT SECTION EDITORS: SOON BAHRAMI, MD; CARRIE ANN R. CUSACK, MD; SENAIT W. DYSON, MD; MOLLY A. HINSHAW, MD; ARNI K. KRISTJANSSON, MD
Histologic examination of the biopsy specimen showed a focal invagination of the epidermis with a column of parakeratotic cells in the horny layer (cornoid lamella). Granular layer underlying the lamella was absent, and continuous epidermis was thinned. Superficial dermis showed a sparse lymphocytic infiltrate without solar elastosis changes (Figure 2 and 3). Tretinoin, 0.025%, was applied once a day topically to the lesions with partial improvement after 3 months. Sun protection was also recommended.
Long-term Progression Facial Plaque —Diagnosis. Arch Dermatol. 2011;147(9):1097-1102. doi:10.1001/archdermatol.2011.252-b