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Feb 2012

Hyperpigmented Asymptomatic Macule in a Fingertip With Suspicious Dermoscopic Pattern —Diagnosis

Author Affiliations
 

SECTION EDITOR: MARY S. STONE, MD; ASSISTANT SECTION EDITORS: SOON BAHRAMI, MD; CARRIE ANN R. CUSACK, MD; SENAIT W. DYSON, MD; MOLLY A. HINSHAW, MD; ARNI K. KRISTJANSSON, MD

Arch Dermatol. 2012;148(2):247-252. doi:10.1001/archderm.148.2.247-e

With hematoxylin-eosin staining we found normal skin with a large amount of pale cells, singly or in small clusters within all epidermis layers. Each of those cells was larger than surrounding keratinocytes, round cells with a central oval pyknotic nucleus surrounded by a clear halo (Figure 3). No viral inclusions were found. Findings from Immunohistochemical analysis were negative with carcinoembryonic antigen, epithelial membrane antigen, cytokeratin 7, and S-100 protein and positive with cytokeratin AE1/AE3.

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