SECTION EDITOR: MARY S. STONE, MD; ASSISTANT SECTION EDITORS: SOON BAHRAMI, MD; CARRIE ANN R. CUSACK, MD; SENAIT W. DYSON, MD; MOLLY A. HINSHAW, MD; ARNI K. KRISTJANSSON, MD
A 57-year-old man from Wisconsin developed petechiae and purpuric papules and vesicles on his lower legs within 3 days of returning from traveling abroad. He was treated with cephalexin for presumed arthropod assault and within a week developed malaise, leg edema, fatigue, and headache. He had no fever, chills, nausea, vomiting, myalgias, or arthralgias. His medical history included hypertension and dyslipidemia, which were well controlled medically. He had mostly blanchable 2-mm papules scattered on the ankles and 2 larger areas of macular erythema surmounted by eschar on the right calf (Figure 1). The lower legs had 2+ pitting edema. He had no adenopathy. His hands and feet were uninvolved.
Hinshaw M, Lee LH, Troy J. Purpura, Eschars, and Leg Edema in a Traveler —Quiz Case. Arch Dermatol. 2012;148(2):247-252. doi:10.1001/archderm.148.2.247-b