Raynaud syndrome is a vasospastic disorder of the fingers, toes, and other body sites often associated with exposure to cold temperatures or emotional stress.1- 3 Although responses to pharmacologic therapies are helpful, some cases are recalcitrant, leading to persistent pain and ulceration.
Smith L, Polsky D, Franks AG. Botulinum Toxin-A for the Treatment of Raynaud Syndrome. Arch Dermatol. 2012;148(4):426-428. doi:10.1001/archdermatol.2011.1144