SECTION EDITOR: MARY S. STONE, MD; ASSISTANT SECTION EDITORS: SOON BAHRAMI, MD; CARRIE ANN R. CUSACK, MD;c SENAIT W. DYSON, MD; MOLLY A. HINSHAW, MD; ARNI K. KRISTJANSSON, MD
Histopathologic examination with hematoxylin-eosin stain showed parakeratosis and an irregular hyperplasia composed of clear cells with bright cytoplasm and regular nuclei. Spongiosis was observed, and neutrophils were present throughout the epidermis. Dermal vessels were tortuous and ectatic with a moderate lymphohistiocytic infiltrate. Periodic acid–Schiff staining revealed the presence of large amounts of glycogen within the cells.
The patient refused surgical treatment and continued applying topical steroids. At last follow-up, there was minimal regression of the lesion.
A 26-Year-Old Man With an Eczematous Lesion on the Nipple—Diagnosis. Arch Dermatol. 2012;148(5):641-646. doi:10.1001/archderm.148.5.642-b