SECTION EDITOR: MICHAEL BIGBY, MD; ASSISTANT SECTION EDITORS: OLIVIER CHOSIDOW, MD, PhD; ROBERT P. DELLAVALLE, MD, PhD, MSPH; DAIHUNG DO, MD; URBÀ GONZÁLEZ, MD, PhD; CATALIN M. POPESCU, MD, PhD; HYWEL WILLIAMS, MSc, PhD, FRCP
Commentary on: Atopic dermatitis and the hygiene hypothesis revisitedFlohr C, Yeo L Curr Probl Dermatol. 2011;41:1-34
Question: Is there evidence to support an association between atopic dermatitis (AD) and hygiene as it relates to microbial burden? Does the literature support a link between any particular infectious or anti-infectious (ie, antibiotics, vaccinations) agent and AD?
Data Sources: A systematic review of the literature was performed using studies identified via a MEDLINE search from 1966 until June 2010. Search findings were supplemented by a hand search of references contained within studies located by MEDLINE search. 49 new studies were deemed suitable for inclusion.
Dickman M, Dawson AL, Dellavalle RP. The Relationship Between Hygiene and Microbial Burden in Atopic Dermatitis Risk Based on a Systematic Review. Arch Dermatol. 2012;148(8):936-938. doi:10.1001/archdermatol.2012.1410