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Aug 2012

A Growing Pigmented Lesion in a Child With a History of Bone Marrow Transplant and Irradiation—Diagnosis

Author Affiliations
 

SECTION EDITOR: MARY S. STONE, MD; ASSISTANT SECTION EDITORS: SOON BAHRAMI, MD; CARRIE ANN R. CUSACK, MD; MOLLY A. HINSHAW, MD; ARNI K. KRISTJANSSON, MD; LORI D. PROK, MD

Arch Dermatol. 2012;148(8):947-952. doi:10.1001/archderm.148.8.947-g

Histopathologic examination of the biopsy specimen revealed aggregates of basaloid cells with peripheral palisading of nuclei within the dermis and along the undersurface of the epidermis. Prominent melanin was present within the basaloid cell aggregates and the stroma. There was a focal erosion of the epidermis and an infiltrate of mononuclear cells. All margins of the excision were found to be free of tumor, and the patient was therefore followed clinically, initially with skin examinations every 6 months.

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