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Sep 2012

Chronic Hyperpigmented Scaly Plaques—Diagnosis

Author Affiliations
 

SECTION EDITOR: MARY S. STONE, MD; ASSISTANT SECTION EDITORS: SOON BAHRAMI, MD; CARRIE ANN R. CUSACK, MD; SENAIT W. DYSON, MD; MOLLY A. HINSHAW, MD; ARNI K. KRISTJANSSON, MD

Arch Dermatol. 2012;148(9):1073-1078. doi:10.1001/archderm.148.9.1073-e

Histologic examination of the biopsy specimen revealed a loss of epidermal ridge pattern, a decreased granular cell layer, hyperkeratosis, and increased pigmentation of basal keratinocytes, consistent with PR (Figure 3). Our patient was symptomatically treated with topical retinoid cream and a moisturizer for several months, with no subjective or objective improvement. A thorough workup did not reveal any internal disease or malignant process. There was no change in her health status during a 1-year follow-up period.

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