SECTION EDITOR: MICHAEL BIGBY, MD; ASSISTANT SECTION EDITORS: OLIVIER CHOSIDOW, MD, PhD; ROBERT P. DELLAVALLE, MD, PhD, MSPH; DAIHUNG DO, MD; URBÀ GONZÁLEZ, MD, PhD; CATALIN M. POPESCU, MD, PhD; HYWEL WILLIAMS, MSc, PhD, FRCP
Commentary on: Two-centimeter vs 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm: a randomised, multicentre trial Gillgren P, Drzewiecki KT, Niin M, et al Lancet. 2011;378(9803):1635-1642.
Question: In patients with clinical stage IIA through IIC cutaneous melanoma thicker than 2 mm, is survival different for a 2-cm local excision margin compared with a 4-cm excision margin?
Design: Randomized controlled trial. The trial was not masked at any stage.
Sladden MJ. Sufficiency and Safety of 2-cm Excision Margin for Stage IIA Through Stage IIC Cutaneous Melanoma. Arch Dermatol. 2012;148(10):1197-1198. doi:10.1001/archdermatol.2012.2682