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Dec 2012

Circumscribed Acral Hypokeratosis: Successful Treatment of a Potentially Premalignant Condition

Author Affiliations

Author Affiliations: Department of Dermatology, Geisinger Medical Center, Danville, Pennsylvania (Drs Butler and Marks); Case Western Reserve University School of Medicine, Cleveland, Ohio (Ms Kiracofe).

Arch Dermatol. 2012;148(12):1427-1428. doi:10.1001/archdermatol.2012.2919

Circumscribed acral hypokeratosis (CAH) is a rare benign dermatosis of unknown origin first described in 2002.1 This uncommon dermatosis is seen predominantly on the palms of adult women with a mean age of 65 years.2 Lesions have a predilection for the thenar or hypothenar eminence of the predominant palm and less frequently on the soles. Typically, the lesions are solitary, but multiple lesions have been reported.

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