Dec 2012

A Variant of AESOP Syndrome (Adenopathy and Extensive Skin Patch Overlying a Plasmacytoma) in a Malignant Blue-Cell Tumor

Author Affiliations

Author Affiliations: Department of Dermatology, University of Utah, Salt Lake City.

Arch Dermatol. 2012;148(12):1431-1432. doi:10.1001/archdermatol.2012.2858

A 53-year-old man was referred in 1998 for a pruritic eruption on his central chest of 8 months' duration. He reported a sensation of bulging over his lower sternum. On examination, he had a sharply demarcated, indurated, erythematous plaque on the central chest (Figure 1) and bilateral axillary lymphadenopathy. A biopsy specimen showed a nonspecific dermal proliferation of vascular structures (CD34+) with pleomorphic and multinucleated histiocytes (CD68+) and myofibroblasts (Figure 2). Results of immunostaining for S100, factor XIIIA, keratin, estrogen receptor, and progesterone receptor were negative. Tissue cultures were negative.

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