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February 2013

Diffuse Dystrophic Calcinosis Cutis of the Scalp in a Patient With Scalp Discoid Lupus Erythematosus and Systemic Lupus Erythematosus

Author Affiliations

Author Affiliations: Departments of Dermatology (Drs Eastham, Velez, and Vleugels) and Radiology (Dr Chesebro); Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; and Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham (Dr Townsend).

JAMA Dermatol. 2013;149(2):246-248. doi:10.1001/jamadermatol.2013.1420

Dystrophic calcinosis cutis (CC) is the deposition of calcium in previously damaged tissue despite normal systemic calcium metabolism. This phenomenon has been observed in autoimmune connective tissue diseases, including systemic sclerosis, adult and juvenile dermatomyositis, rheumatoid arthritis, and mixed connective tissue disease.1 It is less commonly associated with systemic lupus erythematosus (SLE),1 and even more rarely with subacute cutaneous lupus erythematosus (SCLE)2 and discoid lupus erythematosus (DLE).3 Herein we describe the first reported case to our knowledge of diffuse scalp dystrophic CC in the setting of scalp DLE and SLE.

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