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Editor's Note
March 2013

Lack of Significant Difference Among Antifungal Agents in Dermatophytosis

JAMA Dermatol. 2013;149(3):349. doi:10.1001/jamadermatol.2013.1734

The statistical methods used in this study are very complex. Therefore, JAMA Dermatology sent the manuscript out for statistical review. The conclusions of the meta-analysis, however, were quite simple. Pooled data failed to demonstrate significant differences among the antifungals for the outcome of mycologic cure at the end of treatment. This result is consistent with those of other published systematic reviews. Butenafine, naftifine, and terbinafine were significantly more efficacious for the outcome of sustained cure than were antifungals with which they were compared.

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