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JAMA Dermatology Clinicopathological Challenge
May 2014

Odd-Looking Hair and Progressive Alopecia in Mother and Son

Author Affiliations
  • 1Department of Dermatology, Venereology, and Allergology, University Hospital Würzburg, Würzburg, Germany
  • 2Institute of Human Genetics, University of Bonn, Bonn, Germany
JAMA Dermatol. 2014;150(5):567-568. doi:10.1001/jamadermatol.2013.8078

A woman in her 50s complained about diffuse hair loss for years. Her scalp hair was sparse in early childhood but afterwards grew strong and coarse and remained so for decades. On clinical examination, her shoulder-length, black scalp hair appeared hefty. However, pronounced bilateral frontoparietal recession of the hairline and diffuse alopecia of the crown and vertex were noted. The surface of the scalp was somewhat irregular but lacked inflammatory changes. Eyebrows, eyelashes, and axillary and pubic hair were sparse.

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