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April 2014

Strange Bedfellows

Author Affiliations
  • 1Retired
  • 2Columbia University, New York, New York
  • 3private practice, Pembroke Pines, Florida
JAMA Dermatol. 2014;150(4):365. doi:10.1001/jamadermatol.2013.9136

Brünauer-Fuhs-Siemens syndrome, or keratosis palmoplantaris striata type 1 (OMIM 148700), is caused by mutations in desmoglein 1. Between 1924 and 1929, 3 German-speaking dermatologists described this disease.13 While their names are always grouped together in this eponym, it is difficult to imagine a more unlikely trio.

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