Venous leg ulcers (VLUs) are common, affecting upward of 1% of adults and with increasing incidence and prevalence with advancing age. Venous leg ulcers are associated with reduced quality of life and significant health care costs in addition to sustained ambulatory venous pressure (venous hypertension), which most often results from thrombosis and/or valve disease, affecting the superficial, perforator, or deep veins. As a result, calf muscle pump dysfunction ensues, leading to ulcer formation. Standard care with multilayered compression wraps is aimed at reversing these changes, and application of well-delivered compression achieves healing in up to 75% of patients.
Kirsner RS. Compression of Venous UlcersStandardizing Standard Care. JAMA Dermatol. 2014;150(7):736-737. doi:10.1001/jamadermatol.2014.330