The use of recombinant granulocyte colony-stimulating factor (G-CSF) therapy has been associated with various cutaneous reactions, including neutrophilic dermatitis, folliculitis, vasculitis, and exacerbation of psoriasis.1 Because these cutaneous manifestations have been reported in patients who have underlying diseases and/or who have been treated with concomitant medications, the imputability of G-CSF might be difficult to assess. We report the cutaneous manifestations that appeared in healthy volunteers after the administration of G-CSF.
Paul C, Giachetti S, Pinquier L, Flageul B, Dubertret L, Calvo F. Cutaneous Effects of Granulocyte Colony-Stimulating Factor in Healthy Volunteers. Arch Dermatol. 1998;134(1):111-112. doi: