A 22-year-old man infected with the human immunodeficiency virus (HIV), with normal CD4 cell counts, presented for evaluation of a cutaneous eruption that had been present on his lower extremities for 2 weeks. Cutaneous examination revealed multiple small, erythematous papules and purpuric papules on the lower part of the legs. Several lesions showed changes of early ulceration. Examination of the skin biopsy specimen confirmed a diagnosis of leukocytoclastic vasculitis.
The patient was taking no medications. The results of extensive laboratory evaluation were essentially normal. The patient was treated with oral colchicine and dapsone, with resolution of his lesions. The patient was then unavailable for follow-up for 4 months.
Soni BP, Williford PM, White WL. Erythematous Nodules in a Patient Infected With the Human Immunodeficiency Virus. Arch Dermatol. 1998;134(2):231-236. doi: