Rosacea is a common dermatologic condition, of unknown cause, that has long been associated with dyspepsia. Recent reports have suggested not only an increased prevalence of Helicobacter pylori in patients with rosacea, but have commented on improvement in the dermatologic condition following administration of antimicrobial therapy to eliminate H pylori .1,2 These observations have not been controlled. Additionally, this association is not uniformly agreed on. Scneider and colleagues3 found no difference between patients with rosacea and controls with respect to positive H pylori serologic test results (49% vs 43%). Similarly, Sharma et al4 found that only 12 (26.7%) of 45 patients with rosacea were positive for H pylori using serologic tests compared with 15 (34.9%) of 43 controls.4 The prevalence of H pylori in the population served by our medical facility is known to be quite low, making this group an ideal one in which to detect an increased prevalence of H pylori in any given subgroup of patients.5 Given this low baseline prevalence of H pylori population characteristics, we sought to determine the prevalence of H pylori in patients with rosacea compared with endoscopically studied controls.
Jones MP, Knable, Jr AL, White MJ, Durning SJ. Helicobacter pylori in Rosacea: Lack of an Association. Arch Dermatol. 1998;134(4):511. doi: