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April 1998

Intralesional Methotrexate in Solitary Keratoacanthoma

Arch Dermatol. 1998;134(4):513-514. doi:

Solitary keratoacanthomas (KAs) form part of the spectrum of squamous cell carcinomas as suggested by immunohistochemical determinations1 or constitute a variant of regressive squamous cell carcinoma, probably by immunological mediation of CD4+ T lymphocytes activated by interleukin 2 and adhesion molecules.2

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