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April 1998

Skin Involvement in Male Breast Carcinoma

Arch Dermatol. 1998;134(4):517-518. doi:

Breast carcinoma in men is an infrequent but potentially serious neoplasm. According to 1995 estimates in the United States, breast carcinoma in men accounted for 0.2% of all cancers in men, and it was the cause of death in 0.08% of all cancer deaths in men.1 The most common form of clinical presentation is a painless, firm, retroareolar mass, associated in a variable frequency with cutaneous changes (eg, ulceration or retraction of the nipple). The diagnosis is suggested by clinical appearance or results of mammography or fine-needle aspiration, but a surgical biopsy is mandatory for confirmation. Infiltrating ductal carcinoma is the predominant histological type of this tumor. Epidemiological features, prognostic factors, survival by stages, pattern of metastasis, treatment, and response to treatment in men are similar to those in women with breast carcinoma. However, breast cancers in men are more likely to respond to hormonal manipulation.2

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