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June 1998

Conservative Clinical Diagnoses in Seborrheic Keratosis

Author Affiliations

Copyright 1998 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1998

Arch Dermatol. 1998;134(6):752-753. doi:

The recent study by Eads et al1 determined a 6.4% error rate in the clinical differential diagnosis of seborrheic keratosis vs malignancy. During the 30-month period beginning April 1, 1995, and ending September 30, 1997, my laboratory processed approximately 18000 specimens of all types. Of this number, 390 specimens were submitted by dermatologists with a clinical diagnosis of seborrheic keratosis. Among these, only 8 (2.03%) were diagnosed histologically as malignant and none were malignant melanomas. This rate (2.03%) is less than the 6.4% rate reported by Eads et al.1

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