Syringolymphoid hyperplasia with alopecia (SLHA) is a rare disease, which was first reported by Sarkany in 1969.1 Clinical features of SLHA include hairless patches with follicular papules. Histopathologic characteristics include a dense lymphohistiocytic infiltrate surrounding hyperplastic eccrine sweat glands and ducts. We report the ninth case of SLHA. Genotypical analysis revealed a biallelic monoclonal rearrangement of the T-cell receptor γ chain gene. This rearrangement provides further evidence that SLHA represents a cutaneous T-cell lymphoma.
Esche C, Sander CA, Zumdick M, Kutzner H, Kind P, Schulte K, Ruzicka T, Lehmann P. Further Evidence That Syringolymphoid Hyperplasia With Alopecia Is a Cutaneous T-Cell Lymphoma. Arch Dermatol. 1998;134(6):753-754. doi: