Off-Center Fold
August 1998

Palmoplantar Hyperkeratotic Plaques

Author Affiliations



Copyright 1998 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1998

Arch Dermatol. 1998;134(8):1019-1024. doi:

The biopsy specimen of the lesion on the sole revealed psoriasiform epidermal proliferation, a few Pautrier microabscesses, and a dense, predominantly T-cell infiltrate in the upper dermis. Some of the lymphocytes had large irregularly shaped hyperchromatic nuclei.

The patient failed to return for scheduled follow-up until 3 months later, by which time there was not much change in the clinical appearance of the acral lesions. However, 2 slightly raised and scaly plaques had developed on his trunk. A biopsy specimen of 1 of the lesions revealed features consistent with incipient mycosis fungoides. Since then, the patient has been unavailable for follow-up.

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