The neurofibromatoses (NF) are a set of genetic disorders that cause tumors to grow along various types of nerves and, in addition, can affect the development of nonnervous tissues such as bones and skin. At least 8 different forms of neurofibromatosis have been described.1 Neurofibromatosis type 1 (NF1) is the more common form of NF, affecting approximately 3500 to 113000 newborns yearly, and it accounts for 90% of the cases of NF.
Fazii P, Passamonti M, Lappa G, Di Mascio R, Ballone E. Prevalence of Neurofibromatosis Type 1 Among the Young Adult Population of Central Italy. Arch Dermatol. 1998;134(10):1303-1304. doi: