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Off-Center Fold
November 1998

Multiple Subcutaneous Nodules on the Torso and Leg

Arch Dermatol. 1998;134(11):1477-1482. doi:

Histologic examination revealed dense leukemic infiltration of the dermis by immature cells, with occasional mitoses.

It is important to review our patient's history. He first sought medical attention in October 1992 because of gastrointestinal bleeding due to antral and colonic angiodysplasia. Peripheral blood cell counts were within the normal range, and a bone marrow biopsy specimen revealed no abnormalities. During follow-up, the patient complained of pruritus and developed a persistent monocytosis with white blood cell counts as high as 30 × 109/L and elevated platelet counts.

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