Aphthous ulcers are common, recurrent, painful, shallow ulcerations of the oral mucosa that usually resolve in 5 to 14 days. Studies have failed to find the precise etiologic factor.
Helicobacter pylori is a gram-negative coccobacillus responsible for 70% of gastric and 90% of duodenal ulcerations and has also been found in the dental plaque of patients with H pylori–related ulcers.1 These findings suggest that
H pylori might also be the etiologic agent in aphthous ulcers.
Chapman MS, Cimis, Sr RJ, Baughman RD. Lack of Association Between Aphthous Ulcers and Helicobacter pylori. Arch Dermatol. 1998;134(12):1634-1635. doi: