An 81-year-old man presented with a 6-month history of an asymptomatic 20-mm nodule on the left side of the mandible (Figure 1). His medical history was significant for cardiac and peripheral vascular disease and multiple squamous cell carcinomas on sun-exposed areas. The findings of the review of his systems were noncontributory.
The dermal nodule was excised via Mohs micrographic surgery with immediate frozen-tissue margin control. Slides were stained with hematoxylin-eosin (Figure 2 and
Figure 3) and antibodies to cytokeratin, epithelial membrane antigen, CD3, and CD20. The patient was referred for otolaryngological examination, including indirect laryngoscopy, the results of which were unremarkable except for an incidental Warthin tumor.
Dudley CM, Snow SN, Voytovich MC, Warner TF, Hartig GK. Enlarging Facial Nodule on an Elderly Patient. Arch Dermatol. 1998;134(12):1627-1632. doi: