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February 2000

Prevention of Nonmelanoma Skin Cancer

Arch Dermatol. 2000;136(2):245-246. doi:10.1001/archderm.136.2.245

NONMELANOMA SKIN cancers (NMSCs) are the most commonly occurring malignant neoplasms in the United States, and recent evidence indicates that their incidence is increasing rapidly.1,2 This dramatic increase in rates has occurred despite a growing understanding of the mechanisms involved in the development of these cancers. Several important causal factors for NMSC are known: UV radiation is dominant, and ionizing radiation and arsenic exposure also may contribute. Progress has also been made in understanding the molecular mechanisms of UV carcinogenesis.3,4

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