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April 2000

Fecal Porphyrin Measurements Are Crucial for Adequate Screening for Porphyrinopathy—Reply

Author Affiliations

Copyright 2000 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2000

Arch Dermatol. 2000;136(4):554. doi:

In reply

We fully agree with the comments of Dr Morton referring to the relevance of fecal porphyrins in the diagnosis of PCT. The presence of heptacarboxylporphryin and isocoproporphyrin in feces even with normal amounts of total porphyrins confirms the diagnosis of PCT.1 Therefore, urine and fecal samples of the population of the study were both collected. Fecal porphyrins were determined later on, and the results will be published. A qualitative test was performed on all samples. No fluorescence was detected indicating increased porphyrin concentration.

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