We would like to thank Dr Morton for carefully reading the editorial, and for raising the question regarding the porphyrin profile in PCT.1 The purpose of our editorial was to highlight the porphyrin profile that is of diagnostic importance to distinguish PCT from other types of porphyrias. While we agree with Dr Morton that uroporphyrin and heptacarboxyl porphyrin levels are also frequently elevated in feces of patients with PCT, this is well described in standard dermatology textbooks, including in a chapter in a recently published textbook.2 Therefore, we did not feel it was necessary to reiterate this information in the editorial.
Lim HW, Kim JJ. Fecal Porphyrin Measurements Are Crucial for Adequate Screening for Porphyrinopathy—Reply. Arch Dermatol. 2000;136(4):554-555. doi: