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Off-Center Fold
June 2000

Tender Nodules on the Legs of a Cardiac Transplant Recipient

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Arch Dermatol. 2000;136(6):791-796. doi:

The biopsy specimen from the left thigh demonstrated an unremarkable epidermis, with an edematous papillary and reticular dermis. There was a moderate interstitial dermal lymphocytic infiltrate, with the greatest intensity in the upper dermis. Occasional large histiocytes within the dermis were noted to contain abundant trophozoites that were consistent with T gondii (Figure 3, arrows). Trophozoites were also noted within the subcutis, without associated reaction.

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