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June 2000

Diffuse and Progressive Papules and Nodules

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Arch Dermatol. 2000;136(6):791-796. doi:

A previously healthy 67-year-old white man presented with a 10-week history of a diffuse asymptomatic cutaneous eruption that began on his trunk and progressed to involve his extremities. His primary care physician initially treated him with topical corticosteroids for presumed dermatitis, with continued worsening of his disease. A review of systems revealed mild fatigue and a 4.5-kg weight loss over a 3-month period.

Physical examination revealed diffusely scattered erythematous and violaceous smooth-surfaced papules and nodules (Figure 1). A biopsy specimen was obtained from a lesion on the right flank (Figure 2 and Figure 3).

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