Lightening or partial clearing of port-wine stains (PWS) in infants has been demonstrated through photocoagulation with the pulsed dye laser (PDL) (wavelength, 585 nm; pulse width, 0.45 milliseconds; spot size, 5-10 mm ; energy fluences, 4-8 J/cm2).1,2 It has been theorized that selective vascular injury could be further optimized by modifying the PDL to include a broader pulse width, a longer wavelength, and higher energy fluences through the use of dynamic cooling spray.3- 5 In this pilot study we used a PDL with modified parameters in the treatment of infants with facial PWS to evaluate the safety and efficacy of this new device.
Geronemus RG, Quintana AT, Lou WW, Kauvar ANB. High-Fluence Modified Pulsed Dye Laser Photocoagulation With Dynamic Cooling of Port-wine Stains in Infancy. Arch Dermatol. 2000;136(7):942-943. doi: