Recalcitrant facial erythema often occurs in adults with atopic dermatitis and resists common therapies, including topical corticosteroids.1 Recently, several authors have reported that short-term use of tacrolimus (FK506) ointment, a newly developed immunosuppressant drug, shows excellent results with recalcitrant facial erythema.2- 5 In the present study, we analyzed the effects of long-term applications of topical tacrolimus on red face conditions.
Sugiura H, Uehara M, Hoshino N, Yamaji A. Long-term Efficacy of Tacrolimus Ointment for Recalcitrant Facial Erythema Resistant to Topical Corticosteroids in Adult Patients With Atopic Dermatitis. Arch Dermatol. 2000;136(8):1062-1063. doi: