Different hair changes have been reported during human immunodeficiency virus infection. In patients with acquired immunodeficiency syndrome, hair may become softer, silky, discolored, and less curled.1 We recently observed a patient with acquired immunodeficiency syndrome whose previously straight hair became curly during highly active antiretroviral treatment (HAART) about 4 months before developing a spinocellular epithelioma.
Colebunders R, Bottieau E, de Mey I. Curly Hair and Lipodystrophy as a Result of Highly Active Antiretroviral Treatment?. Arch Dermatol. 2000;136(8):1064-1065. doi: