The sentinel lymph node (SN) biopsy procedure is accepted worldwide for treatment of melanoma with more than 1 mm invasion depth.1The technique is a minor surgical procedure with rare complications and is usually performed after a diagnostic excisional biopsy of the primary melanoma, because only histologic examination can confirm diagnosis and invasion depth and serves as a criterion for further treatment. In general, diagnostic biopsiesare performed with up to a 10-mm excisional distance from the primary tumor.
Koller J, Rettenbacher L. The Influence of Diagnostic Biopsies on the Sentinel Lymph Node Detection in Cutaneous Melanoma. Arch Dermatol. 2000;136(9):1176. doi: