The biopsy specimen showed necrosis surrounded by a diffuse infiltrate of neutrophilic granulocytes. Broad nonseptate hyphae were observed with Gomori methenamine-silver staining (Figure 3). The fungal culture yielded Rhizomucor pusillus. Evaluations of sputum, bronchoalveolar lavage, cerebrospinal fluid, blood, and urine specimens were negative for fungal organisms at that time. A computed tomographic scan revealed a thickness of the soft tissue of the lateral aspect of the left orbit, with extension to the musculus rectus lateralis. Exophthalmia and displacement of the left eye were also noted. Computed tomographic scans of the brain and sinuses did not reveal any abnormalities.
A Black Necrotic Skin Lesion in an Immunocompromised Patient. Arch Dermatol. 2000;136(9):1165-1170. doi: