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October 2000

KH 1060 for the Treatment of Lichen Planus: A Multicenter, Randomized, Double-blind, Vehicle-Controlled Study

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Copyright 2000 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2000

Arch Dermatol. 2000;136(10):1272. doi:

The treatment of lichen planus (LP) is often controversial and the results, disappointing.1 Most studies are of small series, with only a minority of controlled studies. We compared a new vitamin D3 analog (KH 1060) with the vehicle in the treatment of LP in a prospective, randomized, double-blind, vehicle-controlled, parallel group study. KH 1060 has been shown to inhibit cell proliferation, to induce cell differentiation, and to have a suppressive effect on T-cell activation.24

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