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December 2000

Disseminated Porokeratosis Associated With Chronic Renal Failure: A New Type of Disseminated Porokeratosis?

Arch Dermatol. 2000;136(12):1568-1569. doi:

The porokeratoses are a group of disorders of keratinization characterized histologically by a cornoid lamella. They include disseminated superficial actinic porokeratosis, porokeratosis palmaris plantaris et disseminata, porokeratosis of Mibelli, linear porokeratosis, and punctate porokeratosis.1 Porokeratoses have been associated with acquired immunodeficiency syndrome and treatments such as immunosuppression in cardiac and renal transplant recipients, cancer chemotherapy, corticosteroid use, and psoralen plus UV-A treatment for psoriasis. Exacerbation of porokeratoseswith the use of benzylhydrochlorothiazide has also occurred.2 We report a case in which the onset of disseminated porokeratosis occurred with mild renal failure and progressed with the worsening of the renal failure.

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