Targetoid hemosiderotic hemangioma (THH) is a benign, solitary, targetoid vascular neoplasm occurring on the face, trunk, or extremities of young or middle-aged adults. We report 2 cases of THH observed in a father and his adult son, suggesting a possible familial predilection to develop these lesions.
A 37-year-old man presented with a 3- to 4-year history of a lesion on the right thigh. This lesion intermittently flared with concomitant increase in size, palpability, and violaceous hue. At the time of these flares, the patient noted mild tenderness and a targetoid appearance of the lesion. On examination, a 1.8-cm targetoid violaceous brown plaque with an annular violaceous ring was noted on the right lateral thigh (Figure 1). Results of histologic examination of the biopsy specimen demonstrated prominent, dilated, thin-walled vessels in the papillary dermis. Prominent endothelial cells had a "hobnail" appearance. Perivascular hemosiderin was present (Figure 2).
Christenson L, VanBeek M, Davis D. Targetoid Hemosiderotic Hemangioma Occurring in a Father and Son. Arch Dermatol. 2000;136(12):1571-1572. doi: