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June 2010

Pale Macules, Crusted Papules, and Breathlessness in a Child—Diagnosis

Author Affiliations
 

MARY S.STONEMDSOONBAHRAMIMDCARRIE ANN R.CUSACKMDSENAIT W.DYSONMDMOLLY A.HINSHAWMDVINCENTLIUMD

Arch Dermatol. 2010;146(6):667-672. doi:10.1001/archdermatol.2010.118-b

The skin biopsy specimen demonstrated a dermal infiltrate of large cells with pale cytoplasm and “kidney-shaped” nuclei with prominent epidermal exocytosis. Reactive macrophages, eosinophils, and lymphocytes were present (Figure 2). Infiltrating cells demonstrated immunopositivity for CD1a and S100 protein (Figure 3).

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