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January 2016

Global Quantitative Techniques for Positron Emission Tomographic Assessment of Disease Activity in Cutaneous T-Cell Lymphoma and Response to Treatment

Author Affiliations
  • 1Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia
  • 2Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia
JAMA Dermatol. 2016;152(1):103-105. doi:10.1001/jamadermatol.2015.2706

Fluorodeoxyglucose positron emission tomography (FDG-PET) imaging has been suggested as a useful modality in staging, assessing response to treatment, and detecting disease recurrence in primary cutaneous T-cell lymphoma (CTCL).1 Indices of FDG uptake include conventional measurements such as maximum standardized uptake value (SUVmax) mean SUV (SUVmean) and global measurements such as global metabolic volume (GMV) and global lesion glycolysis (GLG). Some investigators support conventional metrics,2,3 while others have demonstrated greater value in global tumor measurements.4

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