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Comment & Response
November 2015

Concerns About Presence of a Wild-Type BAP1 Allele in Absence of Nuclear Protein Expression

Author Affiliations
  • 1University of Hawai’i Cancer Center, Honolulu, Hawaii
JAMA Dermatol. 2015;151(11):1265-1266. doi:10.1001/jamadermatol.2015.3136

To the Editor As fellow researchers investigating the recently described BAP1 tumor predisposition syndrome (OMIM 614327), we read with great interest the recent report “Multiple Cutaneous Melanomas and Clinically Atypical Moles in a Patient With a Novel Germline BAP1 Mutation” by Gerami et al.1 The evidence of dysplastic nevus syndrome in the presence of germline BAP1 mutations could prove indeed very useful in the clinical setting.

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