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Necrolytic migratory erythema (NME) is a rare paraneoplastic skin disorder, considered the hallmark clinical sign of glucagonoma syndrome. Its recognition allows for early diagnosis of the tumor, which might lead to a better prognosis.1 Additional mucocutaneous features can include angular stomatitis and glossitis.2 We present a case of NME that cleared rapidly following intravenous administration of amino acids.
Thomaidou E, Nahmias A, Gilead L, Zlotogorski A, Ramot Y. Rapid Clearance of Necrolytic Migratory Erythema Following Intravenous Administration of Amino Acids. JAMA Dermatol. 2016;152(3):345-346. doi:10.1001/jamadermatol.2015.3538